JDB, Free Full-Text
Por um escritor misterioso
Descrição
The extracellular matrix (ECM) guides and constrains the shape of the nervous system. In C. elegans, DIG-1 is a giant ECM component that is required for fasciculation of sensory dendrites during development and for maintenance of axon positions throughout life. We identified four novel alleles of dig-1 in three independent screens for mutants affecting disparate aspects of neuronal and glial morphogenesis. First, we find that disruption of DIG-1 causes fragmentation of the amphid sheath glial cell in larvae and young adults. Second, it causes severing of the BAG sensory dendrite from its terminus at the nose tip, apparently due to breakage of the dendrite as animals reach adulthood. Third, it causes embryonic defects in dendrite fasciculation in inner labial (IL2) sensory neurons, as previously reported, as well as rare defects in IL2 dendrite extension that are enhanced by loss of the apical ECM component DYF-7, suggesting that apical and basolateral ECM contribute separately to dendrite extension. Our results highlight novel roles for DIG-1 in maintaining the cellular integrity of neurons and glia, possibly by creating a barrier between structures in the nervous system.
Custom Signature Drink Sign Bar Menu Design – La Design Boutique
Pinpointing the tumor-specific T cells via TCR clusters
WebChatGPT: ChatGPT with internet access
JDB - Quick Guide
The Sphinx, Vol. 49, No.1489, 1942 - The Sphinx - Magazine Collection - Rare Books and Special Collections Digital Library
How to Find Competitors' Keywords with Competitor Keyword Analysis
Journal of Diabetes - Wiley Online Library
JDB Official on X: BREAKING NEWS. IS NOW FREE FOR EVERYONE! CONTRACT RENOUNCED - 0% TAXES. WE HAVE IMPLEMENTED A NEW TIER SYSTEM. ENJOY. / X
JDB ᐈ 130+ slots, + casinos and bonuses.
A spatio-temporally constrained gene regulatory network directed by PBX1/2 acquires limb patterning specificity via HAND2
Fishing Tackle, Lures, Reels, Rods, Gear, Fly
de
por adulto (o preço varia de acordo com o tamanho do grupo)