GPC2-CAR T cells tuned for low antigen density mediate potent
Por um escritor misterioso
Descrição
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
CAR T cells targeting tumor-associated exons of glypican 2 regress neuroblastoma in mice. - Abstract - Europe PMC
CAR-T cells for pediatric malignancies: Past, present, future and nursing implications - ScienceDirect
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors
Full article: B7-H3-targeted CAR-T cell therapy for solid tumors
Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma
JCM, Free Full-Text
Antigen-dependent IL-12 signaling in CAR T cells promotes regional to systemic disease targeting
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors
Mechanisms and strategies for safe chimeric antigen receptor T‐cell activity control - Stock - 2023 - International Journal of Cancer - Wiley Online Library
Strategies to enhance CAR-T persistence, Biomarker Research
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